Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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MM Myeloma Zhan Cluster Number 50 (129 genes) This page contains all miRNA mediated regulation and functional enrichment for MM Myeloma Zhan cluster number 50. Information about myeloma can be found on Wikipedia, and further information about the "MM Myeloma Zhan" dataset can be found in Zhan et al., 2002. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 zzz999 hsa-mir-28-5p Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0002376 immune system process 28 GO:0006570 tyrosine metabolic process 3 GO:0007186 G-protein coupled receptor protein signaling pathway 15 GO:0030154 cell differentiation 37 GO:0032501 multicellular organismal process 73 GO:0032502 developmental process 53 GO:0042487 regulation of odontogenesis of dentine-containing tooth 3 GO:0042592 homeostatic process 22 GO:0045415 negative regulation of interleukin-8 biosynthetic process 2 GO:0048513 organ development 33 GO:0048635 negative regulation of muscle organ development 3 GO:0048731 system development 45 GO:0048856 anatomical structure development 49 GO:0048869 cellular developmental process 37 GO:0048878 chemical homeostasis 17 GO:0050789 regulation of biological process 85 GO:0050896 response to stimulus 79 GO:0065007 biological regulation 91 GO:0065008 regulation of biological quality 38 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-28-5p TargetScan GO:0002376 immune system process 5 28 129 22 0.3298731 hsa-mir-28-5p TargetScan GO:0006570 tyrosine metabolic process 0 3 129 22 0.4320952 hsa-mir-28-5p TargetScan GO:0007186 G-protein coupled receptor protein signaling pathway 2 15 129 22 0.4908872 hsa-mir-28-5p TargetScan GO:0030154 cell differentiation 7 37 129 22 0.2642912 hsa-mir-28-5p TargetScan GO:0032501 multicellular organismal process 12 73 129 22 0.4933223 hsa-mir-28-5p TargetScan GO:0032502 developmental process 11 53 129 22 0.1212327 hsa-mir-28-5p TargetScan GO:0042487 regulation of odontogenesis of dentine-containing tooth 2 3 129 22 0.004406244 hsa-mir-28-5p TargetScan GO:0042592 homeostatic process 3 22 129 22 0.5437294 hsa-mir-28-5p TargetScan GO:0045415 negative regulation of interleukin-8 biosynthetic process 0 2 129 22 0.3131056 hsa-mir-28-5p TargetScan GO:0048513 organ development 6 33 129 22 0.3121971 hsa-mir-28-5p TargetScan GO:0048635 negative regulation of muscle organ development 1 3 129 22 0.07512646 hsa-mir-28-5p TargetScan GO:0048731 system development 7 45 129 22 0.5274168 hsa-mir-28-5p TargetScan GO:0048856 anatomical structure development 8 49 129 22 0.4673538 hsa-mir-28-5p TargetScan GO:0048869 cellular developmental process 7 37 129 22 0.2642912 hsa-mir-28-5p TargetScan GO:0048878 chemical homeostasis 2 17 129 22 0.5866368 hsa-mir-28-5p TargetScan GO:0050789 regulation of biological process 17 85 129 22 0.06524939 hsa-mir-28-5p TargetScan GO:0050896 response to stimulus 14 79 129 22 0.3145344 hsa-mir-28-5p TargetScan GO:0065007 biological regulation 18 91 129 22 0.0576856 hsa-mir-28-5p TargetScan GO:0065008 regulation of biological quality 6 38 129 22 0.4865533

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